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Multiple Choice

AFP can also increase with which other cancer?

Alpha-fetoprotein is a fetal protein produced by the yolk sac and developing liver. In adults, AFP rises with hepatocellular carcinoma and with germ cell tumors that resemble yolk sac tissue. Among the options, testicular germ cell tumors can secrete AFP when they contain a yolk sac (endodermal sinus) component, so AFP levels rise in this cancer. The other cancers listed do not characteristically elevate AFP in routine cases.

Alpha-fetoprotein is a fetal protein produced by the yolk sac and developing liver. In adults, AFP rises with hepatocellular carcinoma and with germ cell tumors that resemble yolk sac tissue. Among the options, testicular germ cell tumors can secrete AFP when they contain a yolk sac (endodermal sinus) component, so AFP levels rise in this cancer. The other cancers listed do not characteristically elevate AFP in routine cases.