Albumin and globulins are synthesized in which organ?

Study liver anatomy and function with our medical students test. Engage with detailed multiple choice questions, each with hints and explanations. Prepare effectively for your test!

Albumin and most globulins are produced by the liver. Hepatocytes in the liver synthesize the majority of circulating plasma proteins, with albumin being a major product that helps maintain oncotic pressure and transport various substances. Many globulins, such as transferrin, ceruloplasmin, and various complement components, are also produced by the liver. Immunoglobulins (antibodies) come mainly from plasma cells in bone marrow and lymphoid tissue, not the liver, but the liver still handles the synthesis of the bulk of the globulin group. The heart, lungs, and kidneys do not serve as the primary sites for producing these circulating plasma proteins.