Albumin and globulins comprise what percentage of total serum protein?

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Albumin and globulins form the bulk of serum proteins. In a normal situation, albumin accounts for about 60% of the total serum protein, while globulins make up about 40%. Together they constitute essentially all of the serum protein, i.e., well over half of it. (Fibrinogen, a plasma protein, is not present in serum after clotting, so it doesn’t alter the serum-protein composition.) Therefore their combined fraction is more than 50%.