An example of hepatocellular disease is which condition?

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Hepatocellular disease means injury to liver cells (hepatocytes) and their function. Viral hepatitis directly damages hepatocytes and triggers immune-mediated inflammation, causing hepatocellular injury and necrosis; this is the classic example of liver parenchymal disease, and it often shows elevated ALT more than other enzymes.

Cholelithiasis involves stones in the gallbladder or bile ducts, which mainly affect the biliary system and can cause cholestasis rather than direct hepatocyte injury. Pancreatitis targets the pancreas, not the liver. Acute kidney injury affects the kidneys, not the liver. Therefore, viral hepatitis best fits hepatocellular disease.