Where is ALP produced?

Study liver anatomy and function with our medical students test. Engage with detailed multiple choice questions, each with hints and explanations. Prepare effectively for your test!

Multiple Choice

Where is ALP produced?

Alkaline phosphatase comes from several tissues, with the main sources being the liver, bone, intestines, and placenta. In adults, the liver’s ALP is produced by the bile duct epithelium and rises with cholestasis; bone ALP comes from osteoblasts during bone formation; intestinal ALP is made by enterocytes in the intestinal mucosa; placental ALP is produced by the placental syncytiotrophoblasts and is especially relevant during pregnancy. Brain and spinal cord have little to no ALP activity, and while other tissues like the kidney, spleen, or lungs may contain some enzyme, they are not major contributors. Therefore, the pattern of production described by those tissues matches ALP's well-established sources.

Alkaline phosphatase comes from several tissues, with the main sources being the liver, bone, intestines, and placenta. In adults, the liver’s ALP is produced by the bile duct epithelium and rises with cholestasis; bone ALP comes from osteoblasts during bone formation; intestinal ALP is made by enterocytes in the intestinal mucosa; placental ALP is produced by the placental syncytiotrophoblasts and is especially relevant during pregnancy. Brain and spinal cord have little to no ALP activity, and while other tissues like the kidney, spleen, or lungs may contain some enzyme, they are not major contributors. Therefore, the pattern of production described by those tissues matches ALP's well-established sources.

More practice questions