Which statement about ALP production is true?

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Alkaline phosphatase is produced by several tissues, not just the liver. In the serum you’re seeing a sum of ALP from different sources: hepatic (bile ducts), osseous (bone), intestinal mucosa, and placental tissue. This matters especially in pregnancy and during growth—the placenta contributes its own ALP isoenzyme, which can raise total ALP levels, and bone-derived ALP is elevated during periods of rapid growth or turnover in children and in certain bone diseases. Because of these multiple sources, ALP is not exclusive to the liver, it can rise in pregnancy, and its levels change with age and physiologic state.

That’s why the statement listing liver, bone, intestines, and placenta as sources is true. The idea that ALP comes only from the liver is incorrect. The notion that ALP is absent in pregnancy is false due to placental production, and the claim that ALP levels don’t change with age is also incorrect since levels are higher in growing individuals and can vary with physiological states like pregnancy.